Chronic intermittent hypoxia aggravates intrahepatic endothelial dysfunction in cirrhotic rats.

Abstract

UNLABELLED Chronic intermittent hypoxia (CIH) occurs with obstructive sleep apnea syndrome (OSAS) and provokes systemic endothelial dysfunction, which is associated with oxidative stress and low nitric oxide (NO) bioavailability. Cirrhotic livers exhibit intrahepatic endothelial dysfunction, which is characterized by an impaired endothelium-dependent… (More)
DOI: 10.1002/hep.26152

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