Chronic intermittent ethanol exposure and its removal induce a different miRNA expression pattern in primary cortical neuronal cultures.

@article{Guo2012ChronicIE,
  title={Chronic intermittent ethanol exposure and its removal induce a different miRNA expression pattern in primary cortical neuronal cultures.},
  author={Yingqiu Guo and Yongxin Chen and Stephanie Carreon and Mei Qiang},
  journal={Alcoholism, clinical and experimental research},
  year={2012},
  volume={36 6},
  pages={1058-66}
}
BACKGROUND Increasing evidence indicates that repeated exposure to and withdrawal from alcohol can result in persistent molecular and cellular adaptations. One molecular adaptation that occurs is the regulation of gene expression, which is thought to lead to the functional alterations that characterize addiction: tolerance, dependence, withdrawal, craving… CONTINUE READING