Chronic intermittent amphetamine pretreatment enhances future appetitive behavior for drug- and natural-reward: interaction with environmental variables.

@article{Nocjar2002ChronicIA,
  title={Chronic intermittent amphetamine pretreatment enhances future appetitive behavior for drug- and natural-reward: interaction with environmental variables.},
  author={Christine Nocjar and Jaak Panksepp},
  journal={Behavioural brain research},
  year={2002},
  volume={128 2},
  pages={189-203}
}
Appetitive behavior for drug and sexual reward is enhanced in animals with a history of amphetamine-experience. The present experiment investigated whether prior exposure to a sensitizing regimen of amphetamine treatment would 'globally' enhance future appetitive behaviors of adult male Sprague-Dawley rats, and whether the drug preexposure-environment or intermittency of administration would affect this development. Reward appetite was compared in drug-experienced versus drug-naive rats using… CONTINUE READING

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