Chronic inflammation imposes aberrant cell fate in regenerating epithelia through mechanotransduction

Abstract

Chronic inflammation is associated with a variety of pathological conditions in epithelial tissues, including cancer, metaplasia and aberrant wound healing. In relation to this, a significant body of evidence suggests that aberration of epithelial stem and progenitor cell function is a contributing factor in inflammation-related disease, although the… (More)
DOI: 10.1038/ncb3290

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