Chronic inflammation drives glioma growth: cellular and molecular factors responsible for an immunosuppressive microenvironment

@inproceedings{Ha2014ChronicID,
  title={Chronic inflammation drives glioma growth: cellular and molecular factors responsible for an immunosuppressive microenvironment},
  author={Edward Ha and Joseph P. Antonios and Horacio Soto and Robert M Prins and Isaac Yang and Noriyuki Kasahara and Linda M Liau and Carol A. Kruse},
  year={2014}
}
This review examines glioma disease initiation, promotion, and progression with a focus on the cell types present within the tumor mass and the molecules responsible for the immunosuppressive microenvironment that are present at each step of the disease. The cell types and molecules present also correlate with the grade of malignancy. An overall type 2 chronic inflammatory microenvironment develops that facilitates glioma promotion and contributes to the neo-vascularization characteristic of… CONTINUE READING

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