Chronic immobilization stress: evidence for decreases of 5-hydroxy-tryptamine immunoreactivity and for increases of glucocorticoid receptor immunoreactivity in various brain regions of the male rat

@article{Kitayama1989ChronicIS,
  title={Chronic immobilization stress: evidence for decreases of 5-hydroxy-tryptamine immunoreactivity and for increases of glucocorticoid receptor immunoreactivity in various brain regions of the male rat},
  author={Isao Kitayama and Antonio Cintra and Ann Marie Janson and Kjell Fuxe and Luigi Francesco Agnati and Peter Eneroth and Martin Aronsson and Anders H{\"a}rfstrand and H. W. M. Steinbush and Theo J. Visser and Menek Goldstein and Wylie Vale and Jan-Ake Gustafsson},
  journal={Journal of Neural Transmission},
  year={1989},
  volume={77},
  pages={93-130}
}
Male rats were exposed to severe 14 day immobilization stress. Body weight, body temperature, food and water intake, behavioral parameters, and serum corticosterone levels were measured during and after the stress period. On the 7th day after cessation of stress the experimental animals together with the control rats were taken to immunocytochemical analysis involving morphometry and microdensitometry of tyrosine hydroxylase (TH), 5-hydroxytryptamine (5-HT), various neuropeptide, and… CONTINUE READING
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