Chronic ifosfamide nephrotoxicity in children.

  title={Chronic ifosfamide nephrotoxicity in children.},
  author={Roderick Skinner},
  journal={Medical and pediatric oncology},
  volume={41 3},
Nephrotoxicity is a frequent complication of treatment with ifosfamide in children. Although renal damage may be acute and reversible, chronic toxicity may develop with potentially serious consequences. Chronic nephrotoxicity due to ifosfamide may lead to a wide variety of subclinical and clinical manifestations. Proximal tubular dysfunction is the commonest presentation, and may lead to a Fanconi syndrome, including hypophosphataemic rickets and proximal renal tubular acidosis. Glomerular… CONTINUE READING


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