Chronic idiopathic neutropenia: Granulopoietic assessment by both marrow culture and granulocyte kinetics

@article{Rickard1980ChronicIN,
  title={Chronic idiopathic neutropenia: Granulopoietic assessment by both marrow culture and granulocyte kinetics},
  author={K. Rickard and R. Brown and E. Yuen and H. Kronenberg},
  journal={American Journal of Hematology},
  year={1980},
  volume={9}
}
Granulopoietic assessment was made in 14 patients with chronic idiopathic neutropenia (CIN) whose neutrophils were consistently less than 1.5 × 109/ liter and in whom there was absence of splenomegaly and recent drug ingestion. Granulopoiesis was studied using a combination of bone marrow culture in nutrient agar and granulocyte kinetics. Agar colony growth assessed bone marrow concentration of granulocyte progenitor cells (GPC) and the proportion of GPC in DNA synthesis by in vitro 3HTdR… Expand
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