Chronic hypobaric hypoxia, patent arterial duct and a new interventional technique to close it

@article{Freudenthal2011ChronicHH,
  title={Chronic hypobaric hypoxia, patent arterial duct and a new interventional technique to close it},
  author={Franz P Freudenthal and Alexander D. Heath and Jorge Villanueva and Janne C. Lopes Mendes and Ximena Vicente and Inge von Alvensleben and Gabriel Echaz{\'u} and Joaqu{\'i}n Castro Navarro and Nora Lang and Rainer Kozlik-Feldmann},
  journal={Cardiology in the Young},
  year={2011},
  volume={22},
  pages={128 - 135}
}
Abstract Background Interventional closure of patent arterial duct has become an accepted alternative to surgical closure. Clinical trial with “Nit-Occlud® PDA-R”. Methods and results To assess the safety and efficacy of the device, we performed a prospective clinical study between June, 2009 and December, 2010 in La Paz, Bolivia. In all, 29 – 22 female patients and 7 male patients – out of 59 patients were selected on the basis of inclusion criteria. The procedures were performed under… 
4 Citations
Multicenter nit‐occlud® PDA‐R patent. Ductus arteriosus occlusion device trial: Initial and six‐month results
  • M. Granja, L. Trentacoste, +4 authors A. Spillman
  • Medicine
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
  • 2015
TLDR
The Nit‐Occlud® PDA‐R trial can close a PDA up to 8 mm in diameter and procedural and six‐month efficacy and safety results are reported.
Implantation of the new Nit‐Occlud PDA‐R device in children below 10 kilogram
TLDR
The Nit‐Occlud PDA‐R® device was developed and especially designed for large PDAs and its most recent experience in children with a body weight lower than 10 kg is reported.
Weaving Indigenous Textile Art Into Cardiac Devices.
TLDR
A multidisciplinary team of weaver artisans, biomedical engineers, and physicians formed to develop a biocompatible occlusive device that would be durable across a lifetime of cardiac cycles, and early experience with the devices suggest excellent clinical outcomes with few or no complications.

References

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Transcatheter Closure of Patent Ductus Arteriosus Among Native High-Altitude Habitants
TLDR
ADO appears to be a suitable device for transcatheter occlusion for most such patients, and failed in one child with pulmonary hypertension because the device could not be properly secured in position in a 6-mm PDA.
Transcatheter Closure of Large Patent Ductus Arteriosus Using the Amplatzer Ductal Occluder
TLDR
From limited experience, ADO is safe and effective for the closure of a large PDA and achieved complete closure at 3 months of follow-up.
Transcatheter closure of large patent ductus arteriosus at high altitude with a novel nitinol device
TLDR
The Nitocclud PDA‐R device is safe and effective and can easily close very large PDAs and has a high rate of complete occlusion within 1 year and is easily retrieved if embolized.
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TLDR
It is described here the first Lebanese experience of percutaneous closure of a large patent ductus arteriosus in a 15-year-old female using the new Amplatzer Duct Occluder system.
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TLDR
A series of ninety-two cases which came to autopsy in which it was shown that the patient had had a patent ductus arteriosus without any other congenital abnormality were presented.
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TLDR
Physiologic and anatomic changes have been demonstrated in healthy children born and living at high altitudes and it is probable that at high altitude hypoxia and pulmonary hypertension, which remain as chronic conditions after birth, are factors related to the patency of ductus arteriosus.
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TLDR
The clinical picture of chronic mountain sickness differs from subacute mountain sickness and resembles other chronic altitude diseases described in China and Kyrgyzstan and the heart and pulmonary circulation in healthy highlanders have distinct features in comparison with residents at sea level.
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