Chronic humoral rejection mediated by anti-HLA-DP alloantibodies: insights into the role of epitope sharing in donor-specific and non-donor specific alloantibodies generation.

Abstract

We report the case of a renal transplanted patient, in whom the detection of a unique anti HLA-DP antibody response preceded the development of chronic humoral rejection. In addition to donor-specific anti-DP alloantibodies, the patient displayed reactions against several non-donor-specific DP antigens (NDSA). Interestingly, we found that all the DP… (More)
DOI: 10.1016/j.trim.2008.12.006

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@article{Thaunat2009ChronicHR, title={Chronic humoral rejection mediated by anti-HLA-DP alloantibodies: insights into the role of epitope sharing in donor-specific and non-donor specific alloantibodies generation.}, author={Olivier Thaunat and William P. Hanf and Val{\'e}rie Dubois and Brigitte McGregor and Gis{\`e}le Perrat and C{\'e}cile Chauvet and Jean-louis Touraine and E. Morelon}, journal={Transplant immunology}, year={2009}, volume={20 4}, pages={209-11} }