Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring

  title={Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring},
  author={Sheau-Fang Ng and R. Lin and D. R. Laybutt and R. Barr{\`e}s and J. A. Owens and M. Morris},
  • Sheau-Fang Ng, R. Lin, +3 authors M. Morris
  • Published 2010
  • Biology, Medicine
  • Nature
  • The global prevalence of obesity is increasing across most ages in both sexes. This is contributing to the early emergence of type 2 diabetes and its related epidemic. Having either parent obese is an independent risk factor for childhood obesity. Although the detrimental impacts of diet-induced maternal obesity on adiposity and metabolism in offspring are well established, the extent of any contribution of obese fathers is unclear, particularly the role of non-genetic factors in the causal… CONTINUE READING
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    Paper Mentions

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