Chronic hepatitis in HBsAg carriers with serum HBV-DNA and anti-HBe.

@article{Bonino1986ChronicHI,
  title={Chronic hepatitis in HBsAg carriers with serum HBV-DNA and anti-HBe.},
  author={Ferruccio Bonino and Floriano Rosina and Mario Rizzetto and Rocco Rizzi and Elisabetta Chiaberge and Regina Tardanico and Francesco Callea and Giorgio Verme},
  journal={Gastroenterology},
  year={1986},
  volume={90 5 Pt 1},
  pages={
          1268-73
        }
}
We compared the clinical and serologic features of 118 hepatitis B surface antigen carriers with hepatitis B e antibody (anti-HBe) followed up for 3-10 yr (mean 6.1 yr), separated according to the presence or absence of hepatitis B virus-deoxyribonucleic acid (HBV-DNA) in serum. The test was performed by molecular hybridization. There were 28 carriers with and 90 without viral DNA. Carriers with serum anti-HBe/HBV-DNA had major liver disease; cirrhosis developed during the follow-up period in 9… CONTINUE READING
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