Chronic hepatitis B: The interplay between intrahepatic lymphocyte population and viral antigens in relation to liver damage.

@article{Giadans2019ChronicHB,
  title={Chronic hepatitis B: The interplay between intrahepatic lymphocyte population and viral antigens in relation to liver damage.},
  author={Cecilia G Giadans and Daniela Alejandra Rios and Beatriz Ameigeiras and Adriana M Pietrantonio and N{\'e}stor L Lucatelli and Leila Haddad and Eduardo G Mullen and Fabiana Oliveira Heinrich and Elena Noem{\'i} De Matteo and Diego Flichman and Pamela Valva and Mar{\'i}a Victoria Preciado},
  journal={Journal of viral hepatitis},
  year={2019},
  volume={26 6},
  pages={
          727-737
        }
}
In Chronic hepatitis B (CHB) infection, virus and immune response interplay is thought to be responsible for pathogenesis. Yet, the impact of each immune cell population and viral protein expression in liver damage is still unknown. Our aim was to study the interplay between intrahepatic immune response and viral activity in relation to CHB liver damage. Immunostaining was performed in 29 liver biopsies from untreated CHB patients to characterize liver infiltrate [Th (CD4+), CTL (CD8+), Treg… CONTINUE READING
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