Chronic hemodynamic overload of the atria is an important factor for gap junction remodeling in human and rat hearts.

@article{RuckerMartin2006ChronicHO,
  title={Chronic hemodynamic overload of the atria is an important factor for gap junction remodeling in human and rat hearts.},
  author={Catherine Rucker-Martin and Paul Ursmar Milliez and Sisareuth Tan and Xavier Decrouy and Michel Recouvreur and Roger Vranckx and Claude Delcayre and Jean-François Renaud and Irene Dunia and Dominique Segretain and St{\'e}phane Nicolas Hatem},
  journal={Cardiovascular research},
  year={2006},
  volume={72 1},
  pages={69-79}
}
OBJECTIVES The expression and distribution of connexins is abnormal in a number of cardiac diseases, including atrial fibrillation, and is believed to favor conduction slowing and arrhythmia. Here, we studied the role of atrial structural remodeling in the disorganization of gap junctions and whether redistributed connexins can form new functional junction channels. METHODS Expression of connexin-43 (Cx43) was characterized by immunoblotting and immunohistochemistry in human right atrial… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 43 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 45 references

Similar Papers

Loading similar papers…