Chronic granulomatous disease in Israel: clinical, functional and molecular studies of 38 patients.

@article{Wolach2008ChronicGD,
  title={Chronic granulomatous disease in Israel: clinical, functional and molecular studies of 38 patients.},
  author={Baruch Wolach and Ronit Gavrieli and Martin de Boer and Giora Gottesman and Josef Ben-Ari and Menachem Rottem and Yechiel Schlesinger and Galia Grisaru-Soen and Amos Etzioni and Dirk Roos},
  journal={Clinical immunology},
  year={2008},
  volume={129 1},
  pages={103-14}
}
Chronic granulomatous disease (CGD) is an innate immunodeficiency due to a genetic defect in one of the NADPH-oxidase components. In the course of 21 years, 38 Israeli CGD patients were diagnosed with 17 gene mutations, seven of which were new. Clinical, functional, and molecular studies were accomplished. Although X-linked recessive (XLR)-CGD is worldwide the most common genotype of the disease (~70%), in our study only 11 patients (29%) suffered from XLR-CGD. In Israel, the higher incidence… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 38 extracted citations

Chronic granulomatous disease.

Hematology/oncology clinics of North America • 2013
View 4 Excerpts
Highly Influenced

A Novel CYBB Mutation in Chronic Granulomatous Disease in Iran.

Iranian journal of allergy, asthma, and immunology • 2016

Similar Papers

Loading similar papers…