Chronic granulomatous disease as a risk factor for autoimmune disease.

  title={Chronic granulomatous disease as a risk factor for autoimmune disease.},
  author={Suk See De Ravin and Nora Naumann and Edward West Cowen and Julia C. Friend and Dianne M Hilligoss and Martha M. Marquesen and James E. Balow and Karyl S. Barron and Maria L. Chanco Turner and John I. Gallin and Harry L Malech},
  journal={The Journal of allergy and clinical immunology},
  volume={122 6},
Chronic granulomatous disease (CGD) is characterized by recurrent infections and granuloma formation. In addition, we have observed a number of diverse autoimmune conditions in our CGD population, suggesting that patients with CGD are at an elevated risk for development of autoimmune disorders. In this report, we describe antiphospholipid syndrome, recurrent pericardial effusion, juvenile idiopathic arthritis, IgA nephropathy, cutaneous lupus erythematosus, and autoimmune pulmonary disease in… CONTINUE READING
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