Chronic fatigue syndrome: new insights and old ignorance

  title={Chronic fatigue syndrome: new insights and old ignorance},
  author={B. Eveng{\aa}rd and Richard S. Schacterle and A L Komaroff},
  journal={Journal of Internal Medicine},
Abstract. Evengård B, Schacterle RS, Komaroff AL (Karolinska Institute at Huddinge University Hospital, Huddinge, Sweden; and Brigham and Women’s Hospital, Harvard Medical School, Boston, USA). Chronic fatigue syndrome: new insights and old ignorance. J Intern Med 1999; 246: 455–469. 
SÌndrome de fatiga crÛnica en niæos y adolescentes
In 1988 The Center for disease Control and prevention (CDC) first established the diagnostic criteria in the United States, with a modification published in 1994.
Cognitive dysfunction in fibromyalgia and chronic fatigue syndrome: New trends and future directions
  • J. Glass
  • Psychology, Medicine
    Current rheumatology reports
  • 2006
Objective cognitive testing demonstrates long-term and working memory impairments and cerebral abnormalities and a pattern of increased neural recruitment during cognitive tasks in fibromyalgia and chronic fatigue syndrome patients.
Women’s Experiences of Stigma in Relation to Chronic Fatigue Syndrome and Fibromyalgia
Coping with stigma was explored and found to comprise both withdrawal and approach strategies, depending on the individual’s circumstances and goals.
Pathogenesis of Chronic Fatigue Syndrome, a Multisystem Hypothesis
This treatise explores the pathogenesis of CFS as it relates to a complex multidimensional systemic process and offers a hypothesis for the disease processes: an up-regulated immune system, affecting mitochondrial dysfunction is described.
Fibromyalgia and overlapping disorders: the unifying concept of central sensitivity syndromes.
  • M. Yunus
  • Medicine
    Seminars in arthritis and rheumatism
  • 2007
Chronic fatigue syndrome: a form of Addison’s disease
  • R. Baschetti
  • Medicine, Psychology
    Journal of internal medicine
  • 2000
To compensate for EvengaÊrd et al.'s failure to mention both the impressive overlap of CFS with Addison's disease and its clinical implications, I summarize here these issues.
Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis and Fibromyalgia : a Social Model of Disability Perspective
A research paper explores the ways in which people living with CFS/ME have experienced psycho-emotional disablism and three overarching themes were identified: “fighting to be heard”; “lack of legitimacy” and “feeling invisible”.
Kindling and Oxidative Stress as Contributors to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.
It is proposed that the kindling and oxidative stress theories provide a heuristic template for better understanding the at times conflicting findings regarding the etiology and pathophysiology of this illness.
Causes of Death Among Patients With Chronic Fatigue Syndrome
The authors analyzed a memorial list tabulated by the National CFIDS Foundation of 166 deceased individuals who had had CFS, finding the three most prevalent causes of death were heart failure, suicide, and cancer, which accounted for 59.6% of all deaths.
Fatigue: Epidemiology and Social/Industrial Aspects
It has been known for a long time that more women than men suffer from this group of illnesses, but little research has focused on the influence of gender.


The epidemiology of chronic fatigue syndrome
  • S. Wessely
  • Psychology
    Epidemiologia e Psichiatria Sociale
  • 1998
This paper is a revision of an earlier paper on the same subject (Wessely, 1995), and will therefore emphasise those studies which take a population or primary care perspective.
History of chronic fatigue syndrome.
  • S. Straus
  • Medicine, Psychology
    Reviews of infectious diseases
  • 1991
This is a review and critique of many of these alternative diagnoses of chronic fatigue syndrome, sufficient to provide a historical background for current thinking about the disorder.
Neuroimaging in chronic fatigue syndrome.
  • H. Cope, A. David
  • Medicine
    Journal of neurology, neurosurgery, and psychiatry
  • 1996
The link between viral infection, the brain, and fatiguing illnesses has a long history and by the spring of 1918 several English cases of encephalitis lethargica had been reported and in the next year the disease was described.
Neuropsychology of chronic fatigue syndrome: a critical review.
The most consistently documented neuropsychological impairments are in the areas of complex information processing speed and efficiency, and general intellectual abilities and higher order cognitive skills are intact.
Cognitive functioning of patients with chronic fatigue syndrome.
Results of the studies discussed in this paper suggest that impaired information processing, rather than primary memory dysfunction, may be at the root of the cognitive problems that afflict so many patients with CFS.
Chronic fatigue syndrome. A practical guide to assessment and management.
The most important starting point is to promote a consistent pattern of activity, rest, and sleep, followed by a gradual return to normal activity; ongoing review of any 'catastrophic' misinterpretation of symptoms and the problem solving of current life difficulties.
Cognitive and mood-state changes in patients with chronic fatigue syndrome.
It is concluded that while acute mononucleosis and infection with Epstein-Barr virus occasionally result in impaired cognition, such changes have not yet been objectively verified in patients with CFS.
Prevalence of fatigue and chronic fatigue syndrome in a primary care practice.
While chronic, debilitating fatigue is common in medical outpatients, CFS is relatively uncommon and depends substantially on the case definition used.