Chronic fatigue syndrome: an update focusing on phenomenology and pathophysiology

@article{Cho2006ChronicFS,
  title={Chronic fatigue syndrome: an update focusing on phenomenology and pathophysiology},
  author={Hyong Jin Cho and Ania Skowera and Anthony J. Cleare and Simon Wessely},
  journal={Current Opinion in Psychiatry},
  year={2006},
  volume={19},
  pages={67–73}
}
Purpose of review Chronic fatigue syndrome is a controversial condition especially concerning its clinical definition and aetiopathogenesis. Most recent research progress has been made in phenomenology and pathophysiology and we focused our review on these two areas. Recent findings The phenomenology research supports the notion of a discrete fatigue syndrome which can be distinguished from depression and anxiety. The current case definition, however, may need an improvement based on empirical… 
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The majority of adolescents with CFS experienced an improvement over time in functional impairment, self-reported fatigue and additional symptoms, and a concurrent improvement of autonomic cardiovascular control.
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This model proposes that CFS is precipitated by life events and/or viral illness in vulnerable individuals, such as those who are genetically predisposed, prone to distress, high achievement, and over or under activity and is effective at significantly reducing fatigue and disability in CFS.
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Exposure to childhood stressors is associated with the subsequent development of fatigue syndromes such as CFS and FM, and related symptoms, and further studies are needed to identify the mechanisms underlying these associations.
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TLDR
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TLDR
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TLDR
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