Chronic exposure to urban air pollution induces structural alterations in murine pulmonary and coronary arteries.

@article{Lemos2006ChronicET,
  title={Chronic exposure to urban air pollution induces structural alterations in murine pulmonary and coronary arteries.},
  author={Miriam Lemos and Soraia V Mohallen and Mari{\^a}ngela Macchione and Marisa Dolhnikoff and Jo{\~a}o Vicente de Assunç{\~a}o and John Godleski and Paulo Hil{\'a}rio Nascimento Saldiva},
  journal={Inhalation toxicology},
  year={2006},
  volume={18 4},
  pages={247-53}
}
Epidemiological studies have shown that air pollution increases cardiovascular morbidity and mortality. Objective markers of cardiovascular risk have also been associated with increases in ambient pollution. This study was designed to assess whether prolonged exposure to ambient levels of air pollution may induce structural alterations of pulmonary and cardiac vessels. Mice were chronically exposed to ambient levels of air pollution in downtown São Paulo, Brazil. The animals were maintained in… CONTINUE READING