Chronic exposure to schistosome eggs reduces serum cholesterol but has no effect on atherosclerotic lesion development.

@article{Flamme2007ChronicET,
  title={Chronic exposure to schistosome eggs reduces serum cholesterol but has no effect on atherosclerotic lesion development.},
  author={Anne Camille La Flamme and Marina C. G. Harvie and David N. Kenwright and Kenneth Cameron and Nicolas J Rawlence and Yee S Low and Steve McKenzie},
  journal={Parasite immunology},
  year={2007},
  volume={29 5},
  pages={259-66}
}
Previous studies have shown that people infected with schistosomiasis have lower levels of serum cholesterol than uninfected controls. To better understand the impact of this parasitic infection on serum cholesterol levels and on atherosclerotic lesion development induced by hypercholesterolemia, apolipoprotein E (ApoE)-deficient mice were chronically exposed to the eggs of Schistosoma mansoni over a period of 16 weeks. Total serum cholesterol and low-density lipoprotein (LDL) were reduced in… CONTINUE READING
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