Chronic exposure to anabolic steroids induces the muscle expression of oxytocin and a more than fiftyfold increase in circulating oxytocin in cattle.

@article{Jager2011ChronicET,
  title={Chronic exposure to anabolic steroids induces the muscle expression of oxytocin and a more than fiftyfold increase in circulating oxytocin in cattle.},
  author={Nadia De Jager and Nicholas J. Hudson and Antonio Reverter and Yonghong Wang and Shivashankar H. Nagaraj and Linda M. Cafe and Paul L. Greenwood and Ross T Barnard and Kritaya P Kongsuwan and Brian P. Dalrymple},
  journal={Physiological genomics},
  year={2011},
  volume={43 9},
  pages={467-78}
}
Molecular mechanisms in skeletal muscle associated with anabolic steroid treatment of cattle are unclear and we aimed to characterize transcriptional changes. Cattle were chronically exposed (68 ± 20 days) to a steroid hormone implant containing 200 mg trenbolone acetate and 20 mg estradiol (Revalor-H). Biopsy samples from 48 cattle (half treated) from longissimus dorsi (LD) muscle under local anesthesia were collected. Gene expression levels were profiled by microarray, covering 16,944 unique… CONTINUE READING
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