Chronic experimental allergic neuritis in Lewis rats.

@article{Adam1989ChronicEA,
  title={Chronic experimental allergic neuritis in Lewis rats.},
  author={A M Adam and Priscilla Atkinson and Susan M. Hall and Richard A. Hughes and Wilson A. Taylor},
  journal={Neuropathology and applied neurobiology},
  year={1989},
  volume={15 3},
  pages={249-64}
}
An experimental chronic relapsing demyelinating neuropathy was produced by immunizing adult Lewis rats with bovine myelin in low (2.5 mg) and high (5 mg) doses, with and without Mycobacterium tuberculosis in the adjuvant. Each regime produced a similar disease course: acute severe hind limb weakness was followed by apparent recovery and then reappearance of mild neurological deficit with occasional spontaneous exacerbations. The partially recovered animals were relatively resistant to… CONTINUE READING

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