Chronic exogenous corticosterone administration generates an insulin-resistant brain state in rats.

Abstract

We investigated whether long-term administration of exogenous corticosterone (CST) or vehicle as daily treatment induces changes in rat behavior and in gene expression of the rat brain insulin signaling pathway and the formation of tau protein. Two groups of male adult rats received daily subcutaneous injections of 26.8 mg/kg CST (CST stress group) or… (More)
DOI: 10.3109/10253890903080379

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