Chronic exercise lowers the defended body weight gain and adiposity in diet-induced obese rats.

@article{Levin2004ChronicEL,
  title={Chronic exercise lowers the defended body weight gain and adiposity in diet-induced obese rats.},
  author={Barry E. Levin and Ambrose A. Dunn-Meynell},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2004},
  volume={286 4},
  pages={R771-8}
}
The effects of running wheel exercise and caloric restriction on the regulation of body weight, adiposity, and hypothalamic neuropeptide expression were compared in diet-induced obese male rats over 6 wk. Compared with sedentary controls, exercising rats had reduced body weight gain (24%), visceral (4 fat pads; 36%) and carcass (leptin; 35%) adiposity but not insulin levels. Hypothalamic arcuate nucleus (ARC) proopiomelanocortin (POMC) mRNA expression was 25% lower, but ARC neuropeptide Y (NPY… CONTINUE READING

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