Chronic ethanol ingestion induces oxidative kidney injury through taurine-inhibitable inflammation.

@article{Latchoumycandane2014ChronicEI,
  title={Chronic ethanol ingestion induces oxidative kidney injury through taurine-inhibitable inflammation.},
  author={Calivarathan Latchoumycandane and Laura E Nagy and Thomas M McIntyre},
  journal={Free radical biology & medicine},
  year={2014},
  volume={69},
  pages={403-16}
}
Chronic ethanol ingestion mildly damages liver through oxidative stress and lipid oxidation, which is ameliorated by dietary supplementation with the anti-inflammatory β-amino acid taurine. Kidney, like liver, expresses cytochrome P450 2E1 that catabolizes ethanol with free radical formation, and so also may be damaged by ethanol catabolism. Sudden loss of kidney function, and not liver disease itself, foreshadows mortality in patients with alcoholic hepatitis [J. Altamirano, Clin… CONTINUE READING
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