Chronic ethanol has region-selective effects on Egr-1 and Egr-3 DNA-binding activity and protein expression in the rat brain.

Abstract

This study focused on the DNA-binding activity and protein expression of the transcription factors Egr-1 and Egr-3 in the rat brain cortex and hippocampus after chronic or acute ethanol exposure. DNA-binding activity was reduced in both regions after chronic ethanol exposure and was restored to the level of the pair-fed group at 16 h of withdrawal. Cortical… (More)

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Cite this paper

@article{Depaz2000ChronicEH, title={Chronic ethanol has region-selective effects on Egr-1 and Egr-3 DNA-binding activity and protein expression in the rat brain.}, author={Iris M. Booth Depaz and Silvia Goodenough and Peter A. Wilce}, journal={Neurochemistry international}, year={2000}, volume={37 5-6}, pages={473-82} }