Chronic epi-inositol has an anxiolytic-like effect in the plus-maze model in rats.

@article{Einat1998ChronicEH,
  title={Chronic epi-inositol has an anxiolytic-like effect in the plus-maze model in rats.},
  author={Haim Einat and Ziva Elkabaz-Shwortz and Hagit Cohen and Ora Kofman and Robert Haim Belmaker},
  journal={The international journal of neuropsychopharmacology},
  year={1998},
  volume={1 1},
  pages={31-34}
}
Behavioural effects of myo-inositol have been demonstrated in animal models of psychiatric disorders and in clinical trials in psychiatric patients. These effects of myo-inositol were thought to be consequences of its being a substrate for the enzyme phosphatidylinositol (PI) synthase. Recently, epi-inositol, an unnatural stereoisomer of myo-inositol that is not a substrate for PI synthase, was found to also have effects similar to those of myoinositol to reverse lithium-pilocarpine seizures… CONTINUE READING
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