Chronic dietary lithium inhibits basal c-fos mRNA expression in rat brain.

@article{Math1995ChronicDL,
  title={Chronic dietary lithium inhibits basal c-fos mRNA expression in rat brain.},
  author={Aleksander A. Math{\'e} and Jeannette C. Miller and Carina Stenfors},
  journal={Progress in neuro-psychopharmacology & biological psychiatry},
  year={1995},
  volume={19 7},
  pages={1177-87}
}
1. Lithium is the most effective prophylactic agent used in the treatment of bipolar disorder. Although the acute effects of lithium include an inhibitory action on the phosphatidylinositol (PI) system, the longer term effects on signal transduction processes linked to this system are poorly understood. 2. An important consequence of activation of receptors linked to the PI pathway is activation of protein kinase C (PKC), which is involved in the induction of the proto-oncogene, c-fos. 3. The… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
3 Extracted Citations
0 Extracted References
Similar Papers