Chronic diarrhea associated with hypogammaglobulinemia and enteropathy in infants and children

  title={Chronic diarrhea associated with hypogammaglobulinemia and enteropathy in infants and children},
  author={D. D. Perlmutter and Alan M. Leichtner and Harvey Goldman and Harland S. Winter},
  journal={Digestive Diseases and Sciences},
In order to define the gastrointestinal manifestations and small intestinal structure and function in a group of infants with chronic nonspecific diarrhea and hypogammaglobulinemia, we retrospectively identified 55 such patients from a population of 518 children evaluated for chronic diarrhea over a 6-year span (10.6%). All patients had IgG levels 2.0sd or more below the mean values for age. Patients with biochemical evidence of protein loss (enteropathy or nephropathy) were excluded. There was… CONTINUE READING


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