Chronic constipation in adults

@article{McCallum2009ChronicCI,
  title={Chronic constipation in adults},
  author={Iain J.D. McCallum and Sarah Ong and Mark A. Mercer-Jones},
  journal={BMJ : British Medical Journal},
  year={2009},
  volume={338}
}
#### Summary points Chronic constipation in adults is a common and often debilitating problem that may present to almost any medical practitioner as it can have many causes. The most recent Rome criteria provide a useful research and clinical tool for defining chronic, functional constipation (box 1).1 For the problem to be described as chronic, the Rome criteria need to have been met for the previous three months, with the onset of symptoms six months prior to diagnosis. We prefer a more… 
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  • Medicine
    Therapeutic advances in gastroenterology
  • 2011
TLDR
Newer prokinetic agents, targeting peristalsis, intestinal secretion and the colonic flora, have been developed for laxative refractory constipation, and the relative indications for each of them are focused on.
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