Chronic colitis induces expression of β-defensins in murine intestinal epithelial cells.


Anti-microbial peptides are important effectors in innate immunity. In the gut they defend against pathogens, shape the commensal microbiota and probably control intestinal homeostasis. Ulcerative colitis (UC), but not Crohn's disease, shows increased expression of inducible β-defensins (hBD-2, hBD-3 and hBD-4) in colonic epithelial cells. Does inducible… (More)
DOI: 10.1111/j.1365-2249.2010.04282.x


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