• DOI:10.1007/s10072-010-0458-3
Corpus ID: 27687609

Chronic cerebro-spinal venous insufficiency (CCSVI) and multiple sclerosis

@article{Ghezzi2010ChronicCV,
  title={Chronic cerebro-spinal venous insufficiency (CCSVI) and multiple sclerosis},
  author={A. Ghezzi and G. Comi and A. Federico},
  journal={Neurological Sciences},
  year={2010},
  volume={32},
  pages={17-21}
}

A. Ghezzi, G. Comi, A. Federico

Published 2010

Medicine

Neurological Sciences

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the CNS caused by the interplay of genetic and environmental factors. In the last years, it has been suggested that an abnormal venous drainage due to stenosis or malformation of the internal jugular and/or azygous veins may play a major pathogenetic role in MS. This abnormality called chronic cerebro-spinal venous insufficiency (CCSVI) could result in increased permeability of blood brain barrier, local iron deposition and… CONTINUE READING

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