Chronic cerebral hypoperfusion: loss of pupillary reflex, visual impairment and retinal neurodegeneration.

@article{Davidson2000ChronicCH,
  title={Chronic cerebral hypoperfusion: loss of pupillary reflex, visual impairment and retinal neurodegeneration.},
  author={Christopher M Davidson and Bruce A. Pappas and W. Dale Stevens and Teresa Fortin and Steffany A. L. Bennett},
  journal={Brain research},
  year={2000},
  volume={859 1},
  pages={96-103}
}
Adult rats underwent permanent bilateral occlusion of the common carotid arteries (2VO) to determine the effect of chronic cerebral ischemia on vision and retina. They were monitored post-surgically for the presence of the pupillary reflex to light. Some rats were tested for 6 months post-surgically on a radial arm maze task and then tested in another water-escape task which explicitly tested visual function. Another group of rats were tested post-surgically for 3 months on a task which… CONTINUE READING
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