Chronic centrifugation (hypergravity) disrupts the circadian system of the rat.

@article{Holley2003ChronicC,
  title={Chronic centrifugation (hypergravity) disrupts the circadian system of the rat.},
  author={Daniel C. Holley and Charles W. Deroshia and M. Antonia Moris Moran and Charles E. Wade},
  journal={Journal of applied physiology},
  year={2003},
  volume={95 3},
  pages={
          1266-78
        }
}
The present study was conducted to evaluate the response of rat deep body temperature (DBT) and gross locomotor activity (LMA) circadian rhythms to acute hypergravity onset and adaptation to chronic (14 day) hypergravity exposure over three gravity intensities (1.25, 1.5, and 2 G). Centrifugation of unanesthetized naive animals resulted in a dramatic acute decrease in DBT (-1.45, -2.40, and -3.09 degrees C for the 1.25, 1.5, and 2.0 G groups, respectively). LMA was suppressed for the duration… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 52 REFERENCES

The Clocks That Time Us: The Circadian Timing System in Mammals

MC Moore-Ede, FM Sulzman, CA. Fuller
  • 1982
VIEW 10 EXCERPTS
HIGHLY INFLUENTIAL

Gravitational biology and the mammalian circadian timing system.

  • Advances in space research : the official journal of the Committee on Space Research
  • 1989
VIEW 13 EXCERPTS
HIGHLY INFLUENTIAL

Hypoxic depression of circadian rhythms in adult rats.

  • Journal of applied physiology
  • 2000
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

The effect of 2G on mouse circadian rhythms.

  • Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology
  • 2000
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Ambient temperature modulates hypoxic-induced changes in rat body temperature and activity differentially.

  • American journal of physiology. Regulatory, integrative and comparative physiology
  • 2001
VIEW 2 EXCERPTS

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