Chronic caffeine treatment attenuates experimental autoimmune encephalomyelitis induced by guinea pig spinal cord homogenates in Wistar rats

@article{Chen2010ChronicCT,
  title={Chronic caffeine treatment attenuates experimental autoimmune encephalomyelitis induced by guinea pig spinal cord homogenates in Wistar rats},
  author={Guo Qian Chen and Xin Wang and Sai Wu and R. Y. Zheng},
  journal={Brain Research},
  year={2010},
  volume={1309},
  pages={116-125}
}
Dysfunction of adenosinergic systems has been implicated in the development of multiple sclerosis in humans and experimental autoimmune encephalomyelitis (EAE) in animals. Caffeine, a non-selective antagonist of adenosine receptors, has been shown to provide protection against myelin oligodendroglia glycoprotein (MOG)-induced EAE in mice. In this study, we showed that chronic caffeine similarly imparts neuroprotection against EAE induced in rats by guinea pig spinal cord homogenates (GPSCH… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 41 CITATIONS

Similar Papers

Loading similar papers…