Chronic but not acute treatment with caffeine attenuates traumatic brain injury in the mouse cortical impact model
@article{Li2008ChronicBN, title={Chronic but not acute treatment with caffeine attenuates traumatic brain injury in the mouse cortical impact model}, author={W. Li and Shuang-Shuang Dai and Jianhong An and P. Li and X. Chen and Ren-ping Xiong and P. Liu and H. Wang and Y. Zhao and M. Zhu and X. Liu and Pei-Fang Zhu and J.-F. Chen and Y. Zhou}, journal={Neuroscience}, year={2008}, volume={151}, pages={1198-1207} }
90 Citations
Influence of chronic caffeine on MDMA-induced behavioral and neuroinflammatory response in mice
- Biology, PsychologyPsychopharmacology
- 2012
Chronic caffeine consumption at low doses exerts anti-inflammatory effects and prevents MDMA-induced neuroinflammation.
Caffeine attenuates brain injury but increases mortality induced by high-intensity blast wave exposure.
- Medicine, BiologyToxicology letters
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Caffeine prevents acute mortality after TBI in rats without increased morbidity
- Biology, MedicineExperimental Neurology
- 2012
Adenosine A3 receptor as a novel therapeutic target to reduce secondary events and improve neurocognitive functions following traumatic brain injury
- Biology, MedicineJournal of neuroinflammation
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The results provide support for the beneficial effects of small molecule A 3 AR agonists to mitigate secondary tissue injury and cognitive impairment following TBI.
Genetic inactivation of adenosine A2A receptors attenuates acute traumatic brain injury in the mouse cortical impact model
- Biology, PsychologyExperimental Neurology
- 2009
Effects of Preinjury and Postinjury Exposure to Caffeine in a Rat Model of Traumatic Brain Injury.
- Medicine, BiologyJournal of caffeine and adenosine research
- 2020
Preexposure of the injured brain to caffeine does not have a major impact on acute and delayed outcome parameters; more importantly, a single acute dose of caffeine after the injury can prevent lethal apnea regardless of chronic caffeine preexposure.
Time-Dependent Bidirectional Neuroprotection by Adenosine 2A Receptor in Experimental Traumatic Brain Injury.
- Medicine, BiologyWorld neurosurgery
- 2019
Chronic caffeine exposure attenuates blast-induced memory deficit in mice.
- Biology, MedicineChinese journal of traumatology = Zhonghua chuang shang za zhi
- 2015
Chronic or high dose acute caffeine treatment protects mice against oleic acid-induced acute lung injury via an adenosine A2A receptor-independent mechanism.
- Biology, MedicineEuropean journal of pharmacology
- 2011
The Many Roles of Adenosine in Traumatic Brain Injury
- Biology
- 2013
This work reports increases in brain interstitial adenosine levels in patients with severe TBI during episodes of ischemia, and suggests that the newly discovered 2,3-cyclic AMP pathway represents an important component of the adenosines response to TBI.
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