Chronic bilateral stimulation of the anterior thalamus of kainate-treated rats increases seizure frequency.

@article{Lado2006ChronicBS,
  title={Chronic bilateral stimulation of the anterior thalamus of kainate-treated rats increases seizure frequency.},
  author={Fred A. Lado},
  journal={Epilepsia},
  year={2006},
  volume={47 1},
  pages={27-32}
}
PURPOSE Electrical stimulation of the anterior nucleus of the thalamus (ANT) is receiving increased attention as a novel means of controlling intractable epilepsy, and has entered human clinical trial. Animal data supporting the anticonvulsant benefit of ANT stimulation, however, has been obtained from acute chemoconvulsant models of epilepsy rather than models of chronic epilepsy with spontaneous seizures. It is unknown whether ANT stimulation is effective in models of chronic epilepsy… CONTINUE READING
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