Chronic benzodiazepine use in general practice patients with depression: an evaluation of controlled treatment and taper-off: report on behalf of the Dutch Chronic Benzodiazepine Working Group.

@article{Zitman2001ChronicBU,
  title={Chronic benzodiazepine use in general practice patients with depression: an evaluation of controlled treatment and taper-off: report on behalf of the Dutch Chronic Benzodiazepine Working Group.},
  author={Frans G Zitman and Jaap E Couv{\'e}e},
  journal={The British journal of psychiatry : the journal of mental science},
  year={2001},
  volume={178},
  pages={
          317-24
        }
}
BACKGROUND Many patients with depression take benzodiazepine drugs long term despite the absence of continuing therapeutic value. AIMS To evaluate a treatment programme involving gradual discontinuation with or without simultaneous selective serotonin reuptake inhibitor (SSRI) prescribing and to determine the long-term outcome after benzodiazepine withdrawal. METHOD Patients went through three phases - change to an equivalent dose of diazepam; subsequent randomisation to either 20 mg of… CONTINUE READING

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