Chronic and Acute Intranasal Oxytocin Produce Divergent Social Effects in Mice

  title={Chronic and Acute Intranasal Oxytocin Produce Divergent Social Effects in Mice},
  author={Huiping Huang and Caterina Michetti and Marta Busnelli and Francesca Manag{\`o} and Sara Sannino and Diego Scheggia and Luca Giancardo and Diego Sona and Vittorio Murino and Bice Chini and Maria Luisa Scattoni and Francesco Papaleo},
Intranasal administration of oxytocin (OXT) might be a promising new adjunctive therapy for mental disorders characterized by social behavioral alterations such as autism and schizophrenia. Despite promising initial studies in humans, it is not yet clear the specificity of the behavioral effects induced by chronic intranasal OXT and if chronic intranasal OXT could have different effects compared with single administration. This is critical for the aforementioned chronic mental disorders that… CONTINUE READING
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