Chronic amphetamine facilitates immunosuppression in response to a novel aversive stimulus: reversal by haloperidol pretreatment.

@article{Basso1999ChronicAF,
  title={Chronic amphetamine facilitates immunosuppression in response to a novel aversive stimulus: reversal by haloperidol pretreatment.},
  author={Ana Mar{\'i}a Basso and Gabriela Gioino and V{\'i}ctor Alejandro Molina and Liliana Marina Cancela},
  journal={Pharmacology, biochemistry, and behavior},
  year={1999},
  volume={62 2},
  pages={307-14}
}
The effect of chronic d-amphetamine sulfate (AMPH) treatment (nine daily injections, 2 mg/kg i.p.) on subsequent foot shock stress-induced immunological response was investigated. In addition, the potential role of a dopaminergic (DA) mechanism in the development of chronic AMPH-induced changes in stress-influenced immune responses was characterized. Exposure to foot shock stress decreased the percentage of T-lymphocytes, and reduced the delayed-type hypersensitivity reaction (DTH) in… CONTINUE READING

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