Chronic alcoholism is associated with an imbalanced production of Th-1/Th-2 cytokines by peripheral blood T cells.

@article{Laso1999ChronicAI,
  title={Chronic alcoholism is associated with an imbalanced production of Th-1/Th-2 cytokines by peripheral blood T cells.},
  author={Francisco Javier Laso and C Iglesias-Osma and Juana Ciudad and Antonio Dopico L{\'o}pez and Isabel Pastor and Alberto Orfao},
  journal={Alcoholism, clinical and experimental research},
  year={1999},
  volume={23 8},
  pages={1306-11}
}
BACKGROUND In the present study, we analyzed, at the intracellular level, the pattern of cytokine secretion by the major CD4+ and CD8strong+ peripheral blood (PB) T-cell subsets in patients with chronic alcoholism, and we correlated it both with the ethanol (EtOH) intake status and with the presence or not of alcoholic liver disease. METHODS For that purpose, a total of 30 chronic alcoholic patients, 10 without liver disease (AWLD group) and 20 diagnosed with alcoholic liver cirrhosis (ALC… CONTINUE READING

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