Chronic administration of the environmental pollutant 4-tert-octylphenol to adult male rats interferes with the secretion of luteinizing hormone, follicle-stimulating hormone, prolactin, and testosterone.

@article{Blake1997ChronicAO,
  title={Chronic administration of the environmental pollutant 4-tert-octylphenol to adult male rats interferes with the secretion of luteinizing hormone, follicle-stimulating hormone, prolactin, and testosterone.},
  author={Charles Blake and Fredric R. Boockfor},
  journal={Biology of reproduction},
  year={1997},
  volume={57 2},
  pages={255-66}
}
4-Tert-octylphenol (OP) is a prevalent environmental pollutant that has been shown to exert both toxic and estrogenic effects on mammalian cells. The effects of OP on the reproductive system of adult male vertebrates are virtually unknown. In the present study, we investigated the effects of chronic exposure to OP on reproductive hormone secretion in the adult male rat and compared the results qualitatively with those observed in other male rats treated chronically with estrogen. We injected… CONTINUE READING

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Effects of chronic exposure to octylphenol on the male rat reproductive system.

Journal of toxicology and environmental health. Part A • 2009
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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association • 2011
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Octylphenol affects morphology and steroidogenesis in mouse tumor Leydig cells.

Toxicology in vitro : an international journal published in association with BIBRA • 2011
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