Chronic Wasting Disease Prion Strain Emergence and Host Range Expansion

Abstract

Human and mouse prion proteins share a structural motif that regulates resistance to common chronic wasting disease (CWD) prion strains. Successful transmission of an emergent strain of CWD prion, H95+, into mice resulted in infection. Thus, emergent CWD prion strains may have higher zoonotic potential than common strains.

DOI: 10.3201/eid2309.161474

Cite this paper

@inproceedings{Herbst2017ChronicWD, title={Chronic Wasting Disease Prion Strain Emergence and Host Range Expansion}, author={Allen J Herbst and Camilo Duque Vel{\'a}squez and Elizabeth Triscott and Judd M. Aiken and Debbie I. McKenzie}, booktitle={Emerging infectious diseases}, year={2017} }