Chronic Varicella‐Zoster Skin Infection Complicating the Congenital Varicella Syndrome

  title={Chronic Varicella‐Zoster Skin Infection Complicating the Congenital Varicella Syndrome},
  author={P Boussault and Franck Boralevi and Laurence Labb{\'e} and Jean Sarlangue and Alain Ta{\"i}eb and Christine L{\'e}aut{\'e}-Labr{\`e}ze},
  journal={Pediatric Dermatology},
Abstract:  Congenital varicella is a rare syndrome arising when a pregnant woman develops varicella before the 24th week of pregnancy. We report an occurrence of congenital varicella syndrome complicated by a chronic varicella zoster virus skin infection in an immunocompetent infant. The chronic verrucous skin infection is puzzling in our patient, as this disease is usually described in immunosuppressed patients. 
Syndromes Associated With Herpes Zoster
Herpes zoster (HZ) or “shingles” is one of the most common neurological conditions worldwide and should be considered in depth while diagnosing the case of herpes zoster.
Viral and Rickettsial Diseases
Skin involvement is generally associated with systemic disease that is often quite serious, and skin lesions are frequently biopsied.
Fetal varicella – diagnosis, management, and outcome
Fetal varicella syndrome (FVS) is due to transplacental infection by the Varicella zoster virus following maternal infection, and damage results from in utero zoster following primary fetal infection.
Varicella zoster virus infection in inflammatory bowel disease
Healthcare providers need to be aware of the various manifestations of primary and secondary VZV infection in immunosuppressed IBD patients and patients should be screened for V zoster virus immunity and vaccinated prior to commencing immunOSuppression.
Chronic mucocutaneous herpes simplex virus and varicella zoster virus infections.
26 – Viral diseases


Severe hydrocephalus associated with congenital varicella syndrome.
An unusual case of congenital varicella syndrome is described in which hydrocephalus was the main consequence and likely represented VZV reactivation in utero.
Epidemiology, outcome and control of varicella-zoster infection
SummaryChickenpox is a mild disease in children, but may be life threatening in immunosuppressed patients, neonates and normal adults, particularly smokers in whom the risk of varicella pneumonia is
Intracerebral varicella-zoster virus reactivation in congenital varicella syndrome.
It is concluded from a case of CVS in a male infant who presented with generalized clonic cerebral seizures at age 4 months that infants with intrauterine VZV infection can suffer intracerebral VzV reactivations that require antiviral treatment.
The Congenital Varicella Syndrome
In the reviewed infants, intrauterine VZV infection has been proved in about 60%.
Chronic verrucous varicella zoster virus skin lesions: clinical, histological, molecular and therapeutic aspects
The outbreak of HIV infection introduced a new phenomenon in varicella zoster virus (VZV) pathology, namely the long‐standing wart‐like skin lesions that are frequently associated with resistance to
Chronic Verrucous Varicella‐Zoster Virus Infection in Patients with the Acquired Immunodeficiency Syndrome (AIDS): Histologic and Molecular Biologic Findings
It is concluded that these unusual verrucous lesions are a chronic manifestation of herpes zoster infection and that the reported presence of other agents in such lesions is probably coincidental.
Varicella and pregnancy.
Chronic varicella-zoster virus skin lesions in patients with human immunodeficiency virus are related to decreased expression of gE and gB.
It is inferred that the VZV behavior in keratinocytes may vary from a latency-like state to a fully developed, productive infection.
Relapse of neonatal herpes simplex virus infection
Neonates with HSV type 2 infections have a greater risk of relapse and have poorer prognoses, and patients with relapse had worse outcomes than those without relapse.