Chronic Sleep Disturbance Impairs Glucose Homeostasis in Rats

@inproceedings{Barf2010ChronicSD,
  title={Chronic Sleep Disturbance Impairs Glucose Homeostasis in Rats},
  author={R. Paulien Barf and Peter Meerlo and Anton J. W. Scheurink},
  booktitle={International journal of endocrinology},
  year={2010}
}
Epidemiological studies have shown an association between short or disrupted sleep and an increased risk for metabolic disorders. To assess a possible causal relationship, we examined the effects of experimental sleep disturbance on glucose regulation in Wistar rats under controlled laboratory conditions. Three groups of animals were used: a sleep restriction group (RS), a group subjected to moderate sleep disturbance without restriction of sleep time (DS), and a home cage control group. To… CONTINUE READING

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Recurrent restriction of sleep and inadequate recuperation induce both adaptive changes and pathological outcomes.

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