Chronic Rhinosinusitis and the Risk of Nasopharyngeal Cancer in a Taiwanese Health Study

@article{Tsou2014ChronicRA,
  title={Chronic Rhinosinusitis and the Risk of Nasopharyngeal Cancer in a Taiwanese Health Study},
  author={Yung-An Tsou and Che-Chen Lin and Chin-Jaan Tai and Ming-Hsui Tsai and T. C. Tsai and Chuan-Mu Chen},
  journal={American Journal of Rhinology \& Allergy},
  year={2014},
  volume={28},
  pages={e168 - e172}
}
Background Although epidemiological and laboratory studies report that chronic inflammatory conditions contribute to the pathogenesis of cancer, it remains controversial whether chronic rhinosinusitis (CRS) results in nasopharyngeal cancer (NPC). Methods Retrospective cohort study was performed from the National Health Insurance (NHI) Taiwan database. This study prospectively examined whether CRS or nasal polyposis is associated with NPC risk in the NHI, a population-based cohort of 231,490… Expand
Risk of nasopharyngeal carcinoma in patients with chronic rhinosinusitis: A nationwide propensity score matched study in Taiwan.
TLDR
Patients with CRS diagnosis have relationship with developing NPC within 1 year of follow-up, but not for longer intervals, which suggests CRS a weak role for NPC. Expand
Risk of depression in patients with chronic rhinosinusitis: A nationwide population-based retrospective cohort study.
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The present study suggests that patients with CRS are at an increased risk of depression, compared with those without CRS, and should pay attention to the psychiatric status of these patients and provide adequate support. Expand
Cancer risk in chronic rhinosinusitis: a propensity score matched case-control cohort study.
TLDR
Cancer risk in CRS patients is significant high than non-CRS patients, especially in head and neck, breast, lung, bladder, colorectal, liver, prostate, and skin cancers. Expand
Chronic Sinusitis and Risk of Head and Neck Cancer in the US Elderly Population
TLDR
Chronic sinusitis is associated with certain HNCs, particularly NPC and NCPSC, which are rare, and most of the increased HNC risk is limited to within 1 year of chronic Sinusitis diagnosis, consistent with surveillance or detection bias. Expand
Nasal Polyps and Future Risk of Head and Neck Cancer: A Nationwide Population-based Cohort Study.
TLDR
Although the absolute cancer incidence is very low, the relative risk of NCPS or nasopharyngeal cancers was significantly higher in older patients with nasal polyps, and further studies are needed to explore the underlying mechanisms and validate the relationships. Expand
Epidemiology of chronic rhinosinusitis, selected risk factors, comorbidities, and economic burden
  • A. Beule
  • Medicine
  • GMS current topics in otorhinolaryngology, head and neck surgery
  • 2015
TLDR
Currently available data regarding the prevalence of CRS is sorted by country and/or region, time point of data collection and the CRS-definition employed, and risk factors like smoking and gastroesophageal reflux are discussed regarding their influence on CRS prevalence. Expand
Sinonasal Tract Inflammation as a Precursor to Nasopharyngeal Carcinoma
TLDR
An association between previous sinonasal inflammatory disease and subsequent NPC is suggested, and further studies are needed to further examine this relationship. Expand
Chronic sinusitis in head and neck cancer patients who received radiotherapy or chemoradiotherapy
TLDR
Higher T stage and concurrent chemotherapy with radiotherapy showed significant association with chronic sinusitis in head and neck cancer patients who receive radiotherapy with concurrent chemotherapy or higher T stage. Expand
Association of Gastroesophageal Reflux With Malignancy of the Upper Aerodigestive Tract in Elderly Patients
TLDR
GERD is associated with the presence of malignancy of the UADT in the US elderly population and this epidemiological association requires further examination to determine causality and diagnostic utility. Expand
Case Definitions for Chronic Rhinosinusitis in Administrative Data: A Systematic Review
TLDR
There is a need to develop a generalizable and validated ICD-based CRS case definition to increase the accuracy of future pharmacoepidemiologic research. Expand
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