Chronic Renal Failure: An Overview from a Pediatric Perspective

@article{Saborio1998ChronicRF,
  title={Chronic Renal Failure: An Overview from a Pediatric Perspective},
  author={Pablo Saborio and Seunghoon Hahn and Satoshi Hisano and Kay Latta and Jon I. Scheinman and James C. M. Chan},
  journal={Nephron},
  year={1998},
  volume={80},
  pages={134 - 148}
}
We present data on the costs and impact of chronic renal failure, the primary renal diseases leading to end-stage renal disease in children, and review the adaptive responses and the pathophysiology and complications of uremia in experimental animals and in man. A treatment strategy is summarized. 

Tables from this paper

Steroid responsive nephrotic syndrome associated with bilateral renal dysplasia

TLDR
A case of a child with bilateral dysplastic kidneys and steroid responsive nephrotic syndrome (SRNS) is reported, an association between renal dysplasia with chronic renal failure and SRNS has not been reported in the English literature.

K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification.

  • Kdoqi Disclaimer
  • Medicine
    American journal of kidney diseases : the official journal of the National Kidney Foundation
  • 2002
TLDR
Initiation of treatment for cardiovascular risk factors at earlier stages of chronic kidney disease should be effective in reducing cardiovascular disease events both before and after the onset of kidney failure.

Can We Prevent Chronic Renal Failure in Children ?

  • Sn
  • Medicine
  • 2004
TLDR
This strategy calls for cooperation of all paediatricians, to identify high risk patients and refer early at the primary care level, proper workup and diagnosis at the secondary level, specific or nonspecific renoprotective treatment at the tertiary level.

Can We Prevent Chronic Renal Failure in Children

TLDR
This strategy calls for cooperation of all paediatricians, to identify high risk patients and refer early at the primary care level, proper workup and diagnosis at the secondary level, specific or nonspecific renoprotective treatment at the tertiary level.

Final height in children with chronic renal failure who have not received growth hormone

TLDR
All efforts should be made to diagnose CRF as early as possible and to try to improve growth before ESRF and RTx and early institution of rhGH therapy should improve FH and improve the chance of achieving near-normal adult height in most patients.

Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation.

TLDR
The clinical effectiveness and cost-effectiveness of rhGH compared with treatment strategies without rhGH for children with GHD, TS, PWS, CRI, SGA and SHOX-D and those born SGA is assessed.

Indications for growth hormone therapy in children

  • J. Kirk
  • Medicine
    Archives of Disease in Childhood
  • 2011
TLDR
There are currently 7 different manufacturers of GH, and while most UK units currently offer free patient choice for GH device, with preliminary evidence indicating that this may improve adherence with therapy, the 30% price difference may limit choice in the future.

Clinical effectiveness and cost-effectiveness of growth hormone in children: a systematic review and economic evaluation.

TLDR
Results suggest that the effects of GH on short-term growth velocity (at 1 year) can range from no improvement to approximately 1 standard deviation above the normal growth velocity for children of the same age.

Avaliação do Estado Nutricional

TLDR
A monitorizacao frequente da ingestao caloricoproteica deve ser iniciada a partir da FG < 60mL/min/1,73 m2, quando ja se observa diminuicao dos niveis sericos de albumina.

References

SHOWING 1-10 OF 234 REFERENCES

Chronic renal failure in infants and children.

Chronic renal insufficiency: conservative management.

This review summarizes the progress which has been achieved in the knowledge and treatment of chronic renal disease

Chronic Renal Insufficiency in Infants and Children

TLDR
A clearer insight into the areas of brain maturation, neurodevelopmental outcome and cognitive function of children with chronic renal insufficiency has been achieved and the aforementioned recent advances are addressed.

Effects of uremia on growth in children.

TLDR
A brief summary of an approach to reverse the effects of uremia on growth, including conservative nutritional management, treatment of anemia with erythropoietin, and selected aspects of growth and development after renal transplantation are concluded.

Dietary management of renal failure in infants and children. Principles of nutritional therapy and some representative diets.

  • J. Chan
  • Medicine
    Clinical pediatrics
  • 1973
TLDR
The present paper not only reviews the known nutritional principles in the control of renal failure, but also offers practical guidelines and diets for good management of uremic infants and children.

Dietary protein intake and the progressive nature of kidney disease: the role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation, and intrinsic renal disease.

TLDR
With the development and increasingly widespread availability of dialysis and transplantation in the past three decades, relatively little attention has been paid to the influence of diet on the progression of renal disease, despite general awareness that renal disease typically follows an inexorably progressive course.

The adolescent with end-stage renal disease.

  • R. Fine
  • Medicine
    American journal of kidney diseases : the official journal of the National Kidney Foundation
  • 1985

Progressive encephalopathy in children with chronic renal insufficiency in infancy.

A retrospective analysis of children with renal failure during the first year of life revealed that 20 of 23 patients developed profound neurologic abnormalities. The encephalopathy was characterized

IgA nephropathy: to treat or not to treat?

TLDR
The recent controlled, double-blind, 2-year study from the Mayo Clinic showed that fish oil slowed the progression of IgA nephropathy, and this will help clarify the role of free oxygen radical release on disease progression, and an understanding on the mechanisms of antioxidants, such as vitamin E, in preventing such renal injury.

Plasma lipid alterations in patients with chronic renal disease.

  • D. Cramp
  • Medicine, Biology
    Critical reviews in clinical laboratory sciences
  • 1982
TLDR
A brief but clinically relevant description of lipoprotein physiology is presented and the role of the plasma lipoproteins in forming an integrated and controlled pathway for lipid metabolism, and how altered regulatory control within the pathway may be associated with pathogenic mechanisms is considered.
...