Chronic Recurrent Multifocal Osteomyelitis (CRMO): Presentation, Pathogenesis, and Treatment

@inproceedings{Hofmann2017ChronicRM,
  title={Chronic Recurrent Multifocal Osteomyelitis (CRMO): Presentation, Pathogenesis, and Treatment},
  author={Sigrun Ruth Hofmann and Franz Kapplusch and Hermann Josef Girschick and Henner Morbach and Jessica Pablik and Polly J Ferguson and Christian M Hedrich},
  booktitle={Current osteoporosis reports},
  year={2017}
}
PURPOSE OF REVIEW Chronic non-bacterial osteomyelitis (CNO) with its most severe form chronic recurrent multifocal osteomyelitis (CRMO) is an autoinflammatory bone disorder. We summarize the clinical presentation, diagnostic approaches, most recent advances in understanding the pathophysiology, and available treatment options and outcomes in CNO/CRMO. RECENT FINDINGS Though the exact molecular pathophysiology of CNO/CRMO remains somewhat elusive, it appears likely that variable defects in the… CONTINUE READING
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Recessive coding and regulatory mutations in FBLIM1 underlie the pathogenesis of sterile osteomyelitis [abstract]. Arthritis Rheumatol

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