Chronic Pain, Dopamine and Depression: Insights from Research on Fibromyalgia

@inproceedings{Ledermann2018ChronicPD,
  title={Chronic Pain, Dopamine and Depression: Insights from Research on Fibromyalgia},
  author={Katharina Ledermann and Chantal Martin-Soelch},
  year={2018}
}
There have been several indications that pain and reward are partly mediated by similar neural pathways in the central nervous system, and that these common pathways are related to both the dopamine (DA) and the opioid systems. Several studies have demonstrated the analgesic effects of rewarding stimuli or activities on positive affective states. On the other hand, chronic pain was shown to impair several aspects of reward processing by possibly altering pain-reward interactions. However, the… CONTINUE READING
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