Chronic Oral Infection with Porphyromonas gingivalis Accelerates Atheroma Formation by Shifting the Lipid Profile

@inproceedings{Maekawa2011ChronicOI,
  title={Chronic Oral Infection with Porphyromonas gingivalis Accelerates Atheroma Formation by Shifting the Lipid Profile},
  author={Tomoki Maekawa and Naoki Takahashi and Koichi Tabeta and Yukari Aoki and Hirotaka Miyashita and Sayuri Miyauchi and Haruna Miyazawa and Takako Eguchi Nakajima and Kazuhisa Yamazaki},
  booktitle={PloS one},
  year={2011}
}
BACKGROUND Recent studies have suggested that periodontal disease increases the risk of atherothrombotic disease. Atherosclerosis has been characterized as a chronic inflammatory response to cholesterol deposition in the arteries. Although several studies have suggested that certain periodontopathic bacteria accelerate atherogenesis in apolipoprotein E-deficient mice, the mechanistic link between cholesterol accumulation and periodontal infection-induced inflammation is largely unknown… CONTINUE READING
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Role of LXRs in control of lipogenesis.

Genes & development • 2000
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